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Loss of RMI2 Increases Genome Instability and Causes a Bloom-Like Syndrome
Bloom syndrome is a recessive human genetic disorder with features of genome instability, growth deficiency and predisposition to cancer. The only known causative gene is the BLM helicase that is a member of a protein complex along with topoisomerase III alpha, RMI1 and 2, which maintains replicatio...
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| Publicado no: | PLoS Genet |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5157948/ https://ncbi.nlm.nih.gov/pubmed/27977684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006483 |
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