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Dissecting non-coding RNA mechanisms in cellulo by single-molecule high-resolution localization and counting

Non-coding RNAs (ncRNAs) recently were discovered to outnumber their protein-coding counterparts, yet their diverse functions are still poorly understood. Here we report on a method for the intracellular Single-molecule High Resolution Localization and Counting (iSHiRLoC) of microRNAs (miRNAs), a co...

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Hlavní autoři: Pitchiaya, Sethuramasundaram, Krishnan, Vishalakshi, Custer, Thomas C., Walter, Nils G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797162/
https://ncbi.nlm.nih.gov/pubmed/23820309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.05.028
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