Downregulation of MicroRNA-9 in iPSC-Derived Neurons of FTD/ALS Patients with TDP-43 Mutations

Transactive response DNA-binding protein 43 (TDP-43) is a major pathological protein in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). There are many disease-associated mutations in TDP-43, and several cellular and animal models with ectopic overexpression of mutant TDP-43 ha...

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Hlavní autoři: Zhang, Zhijun, Almeida, Sandra, Lu, Yubing, Nishimura, Agnes L., Peng, Lingtao, Sun, Danqiong, Wu, Bei, Karydas, Anna M., Tartaglia, Maria C., Fong, Jamie C., Miller, Bruce L., Farese, Robert V., Moore, Melissa J., Shaw, Christopher E., Gao, Fen-Biao
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797144/
https://ncbi.nlm.nih.gov/pubmed/24143176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076055
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