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Downregulation of MicroRNA-9 in iPSC-Derived Neurons of FTD/ALS Patients with TDP-43 Mutations

Transactive response DNA-binding protein 43 (TDP-43) is a major pathological protein in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). There are many disease-associated mutations in TDP-43, and several cellular and animal models with ectopic overexpression of mutant TDP-43 ha...

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Detalhes bibliográficos
Main Authors: Zhang, Zhijun, Almeida, Sandra, Lu, Yubing, Nishimura, Agnes L., Peng, Lingtao, Sun, Danqiong, Wu, Bei, Karydas, Anna M., Tartaglia, Maria C., Fong, Jamie C., Miller, Bruce L., Farese, Robert V., Moore, Melissa J., Shaw, Christopher E., Gao, Fen-Biao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797144/
https://ncbi.nlm.nih.gov/pubmed/24143176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076055
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