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The FTD/ALS-associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila

TDP-43 is an evolutionarily conserved RNA-binding protein currently under intense investigation for its involvement in the molecular pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). TDP-43 is normally localized in the nucleus, but translocated to the cytoplasm i...

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Bibliographic Details
Main Authors: Li, Zhaodong, Lu, Yubing, Xu, Xia-Lian, Gao, Fen-Biao
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526156/
https://ncbi.nlm.nih.gov/pubmed/23042786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds420
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