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Contributions of the Complementarity Determining Regions to the Thermal Stability of a Single-Domain Antibody
Single domain antibodies (sdAbs) are the recombinantly-expressed variable domain from camelid (or shark) heavy chain only antibodies and provide rugged recognition elements. Many sdAbs possess excellent affinity and specificity; most refold and are able to bind antigen after thermal denaturation. Th...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Public Library of Science
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797041/ https://ncbi.nlm.nih.gov/pubmed/24143255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077678 |
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