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Fluorinated Carbohydrates as Lectin Ligands: Dissecting Glycan-Cyanovirin Interactions by (19)F-NMR
NMR spectroscopy and ITC are powerful methods to investigate ligand-protein interactions. Here, we present a versatile and sensitive fluorine NMR approach that exploits the (19)F nucleus of (19)F labeled carbohydrates as a sensor to study glycan binding to lectins. Our approach is illustrated with t...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3796943/ https://ncbi.nlm.nih.gov/pubmed/23447543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201204070 |
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