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New Tools to Study DNA Double-Strand Break Repair Pathway Choice

A broken DNA molecule is difficult to repair, highly mutagenic, and extremely cytotoxic. Such breaks can be repaired by homology-independent or homology-directed mechanisms. Little is known about the network that controls the repair pathway choice except that a licensing step for homology-mediated r...

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Bibliographic Details
Main Authors: Gomez-Cabello, Daniel, Jimeno, Sonia, Fernández-Ávila, María Jesús, Huertas, Pablo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796453/
https://ncbi.nlm.nih.gov/pubmed/24155929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077206
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