Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL

Most relapses in childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) are not predicted using current prognostic features. Here, we determined the co-occurrence and independent prognostic relevance of 3 recently identified prognostic features: BCR-ABL1-like gene signature, deletions in...

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Autors principals: van der Veer, Arian, Waanders, Esmé, Pieters, Rob, Willemse, Marieke E., Van Reijmersdal, Simon V., Russell, Lisa J., Harrison, Christine J., Evans, William E., van der Velden, Vincent H. J., Hoogerbrugge, Peter M., Van Leeuwen, Frank, Escherich, Gabriele, Horstmann, Martin A., Mohammadi Khankahdani, Leila, Rizopoulos, Dimitris, De Groot-Kruseman, Hester A., Sonneveld, Edwin, Kuiper, Roland P., Den Boer, Monique L.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2013
Matèries:
Lymphoid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795461/
https://ncbi.nlm.nih.gov/pubmed/23974192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-462358
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