Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL

Most relapses in childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) are not predicted using current prognostic features. Here, we determined the co-occurrence and independent prognostic relevance of 3 recently identified prognostic features: BCR-ABL1-like gene signature, deletions in...

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Detalhes bibliográficos
Main Authors: van der Veer, Arian, Waanders, Esmé, Pieters, Rob, Willemse, Marieke E., Van Reijmersdal, Simon V., Russell, Lisa J., Harrison, Christine J., Evans, William E., van der Velden, Vincent H. J., Hoogerbrugge, Peter M., Van Leeuwen, Frank, Escherich, Gabriele, Horstmann, Martin A., Mohammadi Khankahdani, Leila, Rizopoulos, Dimitris, De Groot-Kruseman, Hester A., Sonneveld, Edwin, Kuiper, Roland P., Den Boer, Monique L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795461/
https://ncbi.nlm.nih.gov/pubmed/23974192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-462358
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