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Direct Cytosolic Delivery of Polar Cargo to Cells by Spontaneous Membrane-translocating Peptides

Direct cellular entry of potentially useful polar compounds into cells is prevented by the hydrophobic barrier of the membrane. Toward circumventing this barrier, we used high throughput screening to identify a family of peptides that carry membrane-impermeant cargos across synthetic membranes. Here...

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Autors principals: He, Jing, Kauffman, W. Berkeley, Fuselier, Taylor, Naveen, Somanna K., Voss, Thomas G., Hristova, Kalina, Wimley, William C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795295/
https://ncbi.nlm.nih.gov/pubmed/23983125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.488312
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