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Direct Cytosolic Delivery of Polar Cargo to Cells by Spontaneous Membrane-translocating Peptides

Direct cellular entry of potentially useful polar compounds into cells is prevented by the hydrophobic barrier of the membrane. Toward circumventing this barrier, we used high throughput screening to identify a family of peptides that carry membrane-impermeant cargos across synthetic membranes. Here...

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Detalhes bibliográficos
Main Authors: He, Jing, Kauffman, W. Berkeley, Fuselier, Taylor, Naveen, Somanna K., Voss, Thomas G., Hristova, Kalina, Wimley, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795295/
https://ncbi.nlm.nih.gov/pubmed/23983125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.488312
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