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Spontaneous membrane-translocating peptides: influence of peptide self-aggregation and cargo polarity
Peptides that translocate spontaneously across cell membranes could transform the field of drug delivery by enabling the transport of otherwise membrane-impermeant molecules into cells. In this regard, a 9-aminoacid-long motif (representative sequence: PLIYLRLLR, hereafter Translocating Motif 9, TM9...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4645181/ https://ncbi.nlm.nih.gov/pubmed/26567719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16914 |
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