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Spontaneous membrane-translocating peptides: influence of peptide self-aggregation and cargo polarity

Peptides that translocate spontaneously across cell membranes could transform the field of drug delivery by enabling the transport of otherwise membrane-impermeant molecules into cells. In this regard, a 9-aminoacid-long motif (representative sequence: PLIYLRLLR, hereafter Translocating Motif 9, TM9...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Macchi, Sara, Signore, Giovanni, Boccardi, Claudia, Di Rienzo, Carmine, Beltram, Fabio, Cardarelli, Francesco
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645181/
https://ncbi.nlm.nih.gov/pubmed/26567719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16914
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