Φορτώνει......
Functional Specificity of CpG DNA-binding CXXC Domains in Mixed Lineage Leukemia
The MLL CXXC domain binds nonmethylated CpG-containing DNA and is essential for the oncogenic properties of MLL fusion proteins. To determine potential functional promiscuity of similar DNA binding domains, we replaced the MLL CXXC domain in the context of the leukemogenic MLL-AF9 fusion with CXXC d...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Biochemistry and Molecular Biology
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3795288/ https://ncbi.nlm.nih.gov/pubmed/23990460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.474858 |
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