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CpG Island Chromatin Is Shaped by Recruitment of ZF-CxxC Proteins

Most mammalian gene promoters are embedded within genomic regions called CpG islands, characterized by elevated levels of nonmethylated CpG dinucleotides. Here, we describe recent work demonstrating that CpG islands act as specific nucleation sites for the zinc finger CxxC domain–containing proteins...

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Hlavní autoři: Blackledge, Neil P., Thomson, John P., Skene, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809580/
https://ncbi.nlm.nih.gov/pubmed/24186071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a018648
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