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CpG Island Chromatin Is Shaped by Recruitment of ZF-CxxC Proteins

Most mammalian gene promoters are embedded within genomic regions called CpG islands, characterized by elevated levels of nonmethylated CpG dinucleotides. Here, we describe recent work demonstrating that CpG islands act as specific nucleation sites for the zinc finger CxxC domain–containing proteins...

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Detalhes bibliográficos
Main Authors: Blackledge, Neil P., Thomson, John P., Skene, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809580/
https://ncbi.nlm.nih.gov/pubmed/24186071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a018648
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