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A Novel Function of CRL4(Cdt2): REGULATION OF THE SUBUNIT STRUCTURE OF DNA POLYMERASE δ IN RESPONSE TO DNA DAMAGE AND DURING THE S PHASE
DNA polymerase δ (Pol δ4) is a heterotetrameric enzyme, whose p12 subunit is degraded in response to DNA damage, leaving behind a trimer (Pol δ3) with altered enzymatic characteristics that participate in gap filling during DNA repair. We demonstrate that CRL4(Cdt2), a key regulator of cell cycle pr...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Biochemistry and Molecular Biology
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3795253/ https://ncbi.nlm.nih.gov/pubmed/23913683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.490466 |
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