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Oxidative Stress Induced Mitochondrial Protein Kinase A Mediates Cytochrome C Oxidase Dysfunction
Previously we showed that Protein kinase A (PKA) activated in hypoxia and myocardial ischemia/reperfusion mediates phosphorylation of subunits I, IVi1 and Vb of cytochrome c oxidase. However, the mechanism of activation of the kinase under hypoxia remains unclear. It is also unclear if hypoxic stres...
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Main Authors: | , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Public Library of Science
2013
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3795003/ https://ncbi.nlm.nih.gov/pubmed/24130844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077129 |
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