Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code

Structural and biochemical studies have demonstrated that p73, p63 and p53 recognize DNA with identical amino acids and similar binding affinity. Here, measuring transactivation activity for a large number of response elements (REs) in yeast and human cell lines, we show that p53 family proteins als...

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Autori principali: Ciribilli, Yari, Monti, Paola, Bisio, Alessandra, Nguyen, H. Thien, Ethayathulla, Abdul S., Ramos, Ana, Foggetti, Giorgia, Menichini, Paola, Menendez, Daniel, Resnick, Michael A., Viadiu, Hector, Fronza, Gilberto, Inga, Alberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
Soggetti:
Molecular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794606/
https://ncbi.nlm.nih.gov/pubmed/23892287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt657
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