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Dissection of the Dislocation Pathway for Type I Membrane Proteins with a New Small Molecule Inhibitor, Eeyarestatin

The mammalian endoplasmic reticulum (ER)-to-cytosol degradation pathway for disposal of misfolded proteins is an attractive target for therapeutic intervention in diseases that are characterized by impaired protein degradation. The ability to do so is hampered by the small number of specific inhibit...

詳細記述

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書誌詳細
出版年:Mol Biol Cell
主要な著者: Fiebiger, Edda, Hirsch, Christian, Vyas, Jatin M., Gordon, Eva, Ploegh, Hidde L., Tortorella, Domenico
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Cell Biology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC379262/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14767067/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-07-0506
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