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Association with Membrane Protrusions Makes ErbB2 an Internalization-resistant Receptor
In contrast to the epidermal growth factor (EGF) receptor, ErbB2 is known to remain at the plasma membrane after ligand binding and dimerization. However, why ErbB2 is not efficiently down-regulated has remained elusive. Basically, two possibilities exist: ErbB2 is internalization resistant or it is...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC379255/ https://ncbi.nlm.nih.gov/pubmed/14742716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-08-0596 |
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