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Zinc Finger Transcription Factors Designed for Bispecific Coregulation of ErbB2 and ErbB3 Receptors: Insights into ErbB Receptor Biology

Signaling through the ErbB family of tyrosine kinase receptors in normal and cancer-derived cell lines contributes to cell growth and differentiation. In this work, we altered the levels of ErbB2 and ErbB3 receptors, individually and in combination, by using 6-finger and 12-finger synthetic zinc fin...

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Detalhes bibliográficos
Main Authors: Lund, Caren V., Popkov, Mikhail, Magnenat, Laurent, Barbas, Carlos F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265768/
https://ncbi.nlm.nih.gov/pubmed/16199884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.20.9082-9091.2005
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