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Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease

BACKGROUND AND PURPOSE: Transient receptor potential vanilloid type 4 (TRPV4) channels are expressed in brain endothelial cells, but their role in regulating cerebrovascular tone under physiological and pathological conditions is still largely unknown. EXPERIMENTAL APPROACH: Wild-type (WT) mice and...

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Detalhes bibliográficos
Main Authors: Zhang, Luqing, Papadopoulos, Panayiota, Hamel, Edith
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792003/
https://ncbi.nlm.nih.gov/pubmed/23889563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12315
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