Angiotensin IV Receptors Mediate the Cognitive and Cerebrovascular Benefits of Losartan in a Mouse Model of Alzheimer's Disease

The use of angiotensin receptor blockers (ARBs) correlates with reduced onset and progression of Alzheimer's disease (AD). The mechanism depicting how ARBs such as losartan restore cerebrovascular and cognitive deficits in AD is unknown. Here, we propose a mechanism underlying losartan's b...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Royea, Jessika, Zhang, Luqing, Tong, Xin-Kang, Hamel, Edith
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596535/
https://ncbi.nlm.nih.gov/pubmed/28476949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0329-17.2017
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