Angiotensin IV Receptors Mediate the Cognitive and Cerebrovascular Benefits of Losartan in a Mouse Model of Alzheimer's Disease

The use of angiotensin receptor blockers (ARBs) correlates with reduced onset and progression of Alzheimer's disease (AD). The mechanism depicting how ARBs such as losartan restore cerebrovascular and cognitive deficits in AD is unknown. Here, we propose a mechanism underlying losartan's b...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Royea, Jessika, Zhang, Luqing, Tong, Xin-Kang, Hamel, Edith
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596535/
https://ncbi.nlm.nih.gov/pubmed/28476949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0329-17.2017
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