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Simvastatin restored vascular reactivity, endothelial function and reduced string vessel pathology in a mouse model of cerebrovascular disease

Cerebrovascular dysfunction seen in Alzheimer's disease (AD) and vascular dementia (VaD) is multifaceted and not limited to the amyloid-β (Aβ) pathology. It encompasses structural alterations in the vessel wall, degenerating capillaries (string vessels), vascular fibrosis and calcification, fea...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Tong, Xin-Kang, Hamel, Edith
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348394/
https://ncbi.nlm.nih.gov/pubmed/25564230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.226
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