Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges

Topical preexposure prophylaxis interrupts HIV transmission at the site of mucosal exposure. Intermittently dosed vaginal gels containing the HIV-1 reverse transcriptase inhibitor tenofovir protected pigtailed macaques depending on the timing of viral challenge relative to gel application. However,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Smith, James M., Rastogi, Rachna, Teller, Ryan S., Srinivasan, Priya, Mesquita, Pedro M. M., Nagaraja, Umadevi, McNicholl, Janet M., Hendry, R. Michael, Dinh, Chuong T., Martin, Amy, Herold, Betsy C., Kiser, Patrick F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2013
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791780/
https://ncbi.nlm.nih.gov/pubmed/24043812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311355110
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