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Protection against TB with homologous or heterologous protein/vector vaccine approaches is not dependent on CD8(+) T cells

Considerable effort has been directed to develop Mycobacterium tuberculosis (Mtb) vaccines to boost BCG or for those who cannot be immunized with BCG. We hypothesized that CD4(+) and CD8(+) T cell responses with a heterologous prime/boost vaccine approach could induce long-lived vaccine efficacy aga...

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書誌詳細
主要な著者: Baldwin, Susan L., Ching, Lance K., Pine, Samuel O., Moutaftsi, Magdalini, Lucas, Elyse, Vallur, Aarthy, Orr, Mark T., Bertholet, Sylvie, Reed, Steven G., Coler, Rhea N.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791622/
https://ncbi.nlm.nih.gov/pubmed/23904160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301161
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