Intradermal immunization improves protective efficacy of a novel TB vaccine candidate

We have developed the Mycobacterium tuberculosis (Mtb) fusion protein (ID83), which contains the three Mtb proteins Rv1813, Rv3620 and Rv2608. We evaluated the immunogenicity and protective efficacy of ID83 in combination with several emulsion-formulated Toll-like receptor agonists. The ID83 subunit...

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Hlavní autoři: Baldwin, Susan L., Bertholet, Sylvie, Kahn, Maria, Zharkikh, Irina, Ireton, Gregory C., Vedvick, Thomas S., Reed, Steven G., Coler, Rhea N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743149/
https://ncbi.nlm.nih.gov/pubmed/19428920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.03.018
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