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The importance of adjuvant formulation in the development of a TB vaccine

An effective protein based vaccine for tuberculosis (TB) will require a safe and effective adjuvant. There are few adjuvants in approved human vaccines, including Alum and the oil-in-water (o/w) based emulsions MF59 (Novartis Vaccines and Diagnostics), AS03 and AS04 (GlaxoSmith Kline Biologics, GSK)...

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Detalhes bibliográficos
Main Authors: Baldwin, Susan L., Bertholet, Sylvie, Reese, Valerie A., Ching, Lance K., Reed, Steven G., Coler, Rhea N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288309/
https://ncbi.nlm.nih.gov/pubmed/22291184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102696
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