Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes

Acute megakaryoblastic leukemia (AMKL) is more frequently observed in Down syndrome (DS) patients, in whom it is often preceded by a transient myeloproliferative disorder (TMD). The development of DS-TMD and DS-AMKL requires not only the presence of the trisomy 21 but also that of GATA1 mutations. D...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Malinge, Sébastien, Chlon, Tim, Doré, Louis C., Ketterling, Rhett P., Tallman, Martin S., Paietta, Elisabeth, Gamis, Alan S., Taub, Jeffrey W., Chou, Stella T., Weiss, Mitchell J., Crispino, John D., Figueroa, Maria E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790517/
https://ncbi.nlm.nih.gov/pubmed/23980066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-05-503011
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados