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Ovariectomy expands murine short-term hemopoietic stem cell function through T cell expressed CD40L and Wnt10B
Estrogen deficiency expands hemopoietic stem and progenitor cells (HSPCs) and mature blood lineages, but the involved mechanism and the affected HSPC populations are mostly unknown. Here we show that ovariectomy (ovx) expands short-term HSPCs (ST-HSPCs) and improves blood cell engraftment and host s...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3790505/ https://ncbi.nlm.nih.gov/pubmed/23954891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-487801 |
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