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Mechanism for Recognition of an Unusual Mycobacterial Glycolipid by the Macrophage Receptor Mincle
Binding of the macrophage lectin mincle to trehalose dimycolate, a key glycolipid virulence factor on the surface of Mycobacterium tuberculosis and Mycobacterium bovis, initiates responses that can lead both to toxicity and to protection of these pathogens from destruction. Crystallographic structur...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3789947/ https://ncbi.nlm.nih.gov/pubmed/23960080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.497149 |
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