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Defining the conformation of human mincle that interacts with mycobacterial trehalose dimycolate
Trehalose dimycolate, an unusual glycolipid in the outer membrane of Mycobacterium tuberculosis, stimulates macrophages by binding to the macrophage receptor mincle. This stimulation plays an important role both in infection by mycobacteria and in the use of derivatives of mycobacteria as adjuvants...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4211601/ https://ncbi.nlm.nih.gov/pubmed/25028392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwu072 |
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