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Coordinate Regulation of Mature Dopaminergic Axon Morphology by Macroautophagy and the PTEN Signaling Pathway

Macroautophagy is a conserved mechanism for the bulk degradation of proteins and organelles. Pathological studies have implicated defective macroautophagy in neurodegeneration, but physiological functions of macroautophagy in adult neurons remain unclear. Here we show that Atg7, an essential macroau...

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Detalhes bibliográficos
Main Authors: Inoue, Keiichi, Rispoli, Joanne, Yang, Lichuan, MacLeod, David, Beal, M. Flint, Klann, Eric, Abeliovich, Asa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789823/
https://ncbi.nlm.nih.gov/pubmed/24098148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003845
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