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Ligand Clouds around Protein Clouds: A Scenario of Ligand Binding with Intrinsically Disordered Proteins

Intrinsically disordered proteins (IDPs) were found to be widely associated with human diseases and may serve as potential drug design targets. However, drug design targeting IDPs is still in the very early stages. Progress in drug design is usually achieved using experimental screening; however, th...

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Autors principals: Jin, Fan, Yu, Chen, Lai, Luhua, Liu, Zhirong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789766/
https://ncbi.nlm.nih.gov/pubmed/24098099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003249
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