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Ligand Clouds around Protein Clouds: A Scenario of Ligand Binding with Intrinsically Disordered Proteins

Intrinsically disordered proteins (IDPs) were found to be widely associated with human diseases and may serve as potential drug design targets. However, drug design targeting IDPs is still in the very early stages. Progress in drug design is usually achieved using experimental screening; however, th...

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Detalhes bibliográficos
Main Authors: Jin, Fan, Yu, Chen, Lai, Luhua, Liu, Zhirong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789766/
https://ncbi.nlm.nih.gov/pubmed/24098099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003249
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