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Inhibition of Pyrimidine Biosynthesis Pathway Suppresses Viral Growth through Innate Immunity

Searching for stimulators of the innate antiviral response is an appealing approach to develop novel therapeutics against viral infections. Here, we established a cell-based reporter assay to identify compounds stimulating expression of interferon-inducible antiviral genes. DD264 was selected out of...

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書誌詳細
主要な著者: Lucas-Hourani, Marianne, Dauzonne, Daniel, Jorda, Pierre, Cousin, Gaëlle, Lupan, Alexandru, Helynck, Olivier, Caignard, Grégory, Janvier, Geneviève, André-Leroux, Gwénaëlle, Khiar, Samira, Escriou, Nicolas, Desprès, Philippe, Jacob, Yves, Munier-Lehmann, Hélène, Tangy, Frédéric, Vidalain, Pierre-Olivier
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789760/
https://ncbi.nlm.nih.gov/pubmed/24098125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003678
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