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Development of Poly (β-amino esters)-Based Biodegradable Nanoparticles for Non-Viral Delivery of Minicircle DNA

Gene therapy provides a powerful tool for regulating cellular processes and tissue repair. Minicircle (MC) DNA are supercoiled DNA molecules free of bacterial plasmid backbone elements, and have been reported to enhance prolonged gene expression compared to conventional plasmids. Despite the great p...

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Detalhes bibliográficos
Main Authors: Keeney, Michael, Ong, Sang-Ging, Padilla, Amanda, Yao, Zhenyu, Goodman, Stuart, Wu, Joseph C, Yang, Fan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789527/
https://ncbi.nlm.nih.gov/pubmed/23837668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn402657d
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