Highly branched  poly(β-amino ester) delivery of minicircle DNA for transfection of neurodegenerative disease related cells

Current therapies for most neurodegenerative disorders are only symptomatic in nature and do not change the course of the disease. Gene therapy plays an important role in disease modifying therapeutic strategies. Herein, we have designed and optimized a series of highly branched poly(β-amino ester)s...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Shuai, Gao, Yongsheng, Zhou, Dezhong, Zeng, Ming, Alshehri, Fatma, Newland, Ben, Lyu, Jing, O’Keeffe-Ahern, Jonathan, Greiser, Udo, Guo, Tianying, Zhang, Fengzhi, Wang, Wenxin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656726/
https://ncbi.nlm.nih.gov/pubmed/31341171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11190-0
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