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A single center analysis of nucleophosmin in acute myeloid leukemia: value of combining immunohistochemistry with molecular mutation analysis

Mutations of nucleophosmin 1 are frequently found in acute myeloid leukemia and lead to aberrant cytoplasmic accumulation of nucleophosmin protein. Immunohistochemical staining is therefore recommended as the technique of choice in front-line screening. In this study, we assessed the sensitivity and...

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Detalhes bibliográficos
Main Authors: Woolthuis, Carolien M., Mulder, André B., Verkaik-Schakel, Rikst Nynke, Rosati, Stefano, Diepstra, Arjan, van den Berg, Eva, Schuringa, Jan Jacob, Vellenga, Edo, Kluin, Philip M., Huls, Gerwin
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789457/
https://ncbi.nlm.nih.gov/pubmed/23716555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.079806
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