Nucleophosmin mutation analysis in acute myeloid leukaemia: Immunohistochemistry as a surrogate for molecular techniques

BACKGROUND & OBJECTIVES: Mutation of nucleophosmin (NPM1) gene in the absence of FLT3-ITD (FMS related tyrosine kinase 3 - internal tandem duplications) mutation carries a good prognosis in cytogenetically normal acute myeloid leukaemia (AML). NPM1, a multifunctional nucleolar phosphoprotein tha...

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Detalhes bibliográficos
Publicado no:Indian J Med Res
Main Authors: Chopra, Anita, Soni, Sushant, Pati, Haraprasad, Kumar, Dev, Diwedi, Rahul, Verma, Deepak, Vishwakama, Garima, Bakhshi, Sameer, Kumar, Suman, Gogia, Ajay, Kumar, Rajive
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094116/
https://ncbi.nlm.nih.gov/pubmed/27748301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-5916.192027
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