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Three-dimensional cultures modeling premalignant progression of human breast epithelial cells: role of cysteine cathepsins

The expression of the cysteine protease cathepsin B is increased in early stages of human breast cancer. To assess the potential role of cathepsin B in premalignant progression of breast epithelial cells, we employed a 3D reconstituted basement membrane overlay culture model of MCF10A human breast e...

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Detalhes bibliográficos
Main Authors: Mullins, Stefanie R., Sameni, Mansoureh, Blum, Galia, Bogyo, Matthew, Sloane, Bonnie F., Moin, Kamiar
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789365/
https://ncbi.nlm.nih.gov/pubmed/23667900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2012-0252
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