p21-Activated Kinase 1 Coordinates Aberrant Cell Survival and Pericellular Proteolysis in a Three-Dimensional Culture Model for Premalignant Progression of Human Breast Cancer

Overexpression of p21-activated kinase 1 (PAK1) occurs during the progression of human breast cancer. We have investigated the role of PAK1 in the premalignant progression of the MCF10 series of human breast epithelial cell lines. Levels of PAK1 expression and activation increased with premalignant...

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Bibliografiske detaljer
Main Authors: Li, Quanwen, Mullins, Stefanie Roshy, Sloane, Bonnie F, Mattingly, Raymond R
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288538/
https://ncbi.nlm.nih.gov/pubmed/18392133
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