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Imaging Proteolysis by Living Human Breast Cancer Cells

Malignant progression is accompanied by degradation of extracellular matrix proteins. Here we describe a novel confocal assay in which we can observe proteolysis by living human breast cancer cells (BT20 and BT549) through the use of quenched-fluorescent protein substrates. Degradation thus was imag...

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Detalhes bibliográficos
Main Authors: Sameni, Mansoureh, Moin, Kamiar, Sloane, Bonnie F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature America, Inc. 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508086/
https://ncbi.nlm.nih.gov/pubmed/11228542
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