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Live-Cell Imaging of Protease Activity: Assays to Screen Therapeutic Approaches

Methodologies to image and quantify the activity of proteolytic enzymes have been developed in an effort to identify protease-related druggable pathways that are involved in malignant progression of cancer. Our laboratory has pioneered techniques for functional live-cell imaging of protease activity...

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Veröffentlicht in:Methods Mol Biol
Hauptverfasser: Chalasani, Anita, Ji, Kyungmin, Sameni, Mansoureh, Mazumder, Samia H., Xu, Yong, Moin, Kamiar, Sloane, Bonnie F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500169/
https://ncbi.nlm.nih.gov/pubmed/28315254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6850-3_16
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