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H(4)octapa-Trastuzumab: Versatile Acyclic Chelate System for (111)In and (177)Lu Imaging and Therapy
[Image: see text] A bifunctional derivative of the versatile acyclic chelator H(4)octapa, p-SCNBn- H(4)octapa, has been synthesized for the first time. The chelator was conjugated to the HER2/neu-targeting antibody trastuzumab and labeled in high radiochemical purity and specific activity with the r...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3787943/ https://ncbi.nlm.nih.gov/pubmed/23901833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4049493 |
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