Formulation and clinical translation of [(177)Lu]Lu-trastuzumab for radioimmunotheranostics of metastatic breast cancer

Trastuzumab (Herceptin®) is an approved immunotherapeutic agent used for the treatment of metastatic breast cancer over-expressing HER2 antigen receptors. The aim of the present work is to standardize the formulation protocol of [(177)Lu]Lu-trastuzumab addressing various reaction parameters, evaluat...

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Detalhes bibliográficos
Publicado no:RSC Med Chem
Main Authors: Guleria, Mohini, Sharma, Rohit, Amirdhanayagam, Jeyachitra, Sarma, Haladhar D., Rangarajan, Venkatesh, Dash, Ashutosh, Das, Tapas
Formato: Artigo
Idioma:Inglês
Publicado em: RSC 2020
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128050/
https://ncbi.nlm.nih.gov/pubmed/34046615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00319k
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