TNFα Mediated IL-6 Secretion Is Regulated by JAK/STAT Pathway but Not by MEK Phosphorylation and AKT Phosphorylation in U266 Multiple Myeloma Cells

IL-6 and TNFα were significantly increased in the bone marrow aspirate samples of patients with active multiple myeloma (MM) compared to those of normal controls. Furthermore, MM patients with advanced aggressive disease had significantly higher levels of IL-6 and TNFα than those with MM in plateau...

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Main Authors: Lee, Chansu, Oh, Jeong-In, Park, Juwon, Choi, Jee-Hye, Bae, Eun-Kyung, Lee, Hyun Jung, Jung, Woo June, Lee, Dong Soon, Ahn, Kwang-Sung, Yoon, Sung-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787550/
https://ncbi.nlm.nih.gov/pubmed/24151609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/580135
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