TNFα Mediated IL-6 Secretion Is Regulated by JAK/STAT Pathway but Not by MEK Phosphorylation and AKT Phosphorylation in U266 Multiple Myeloma Cells

IL-6 and TNFα were significantly increased in the bone marrow aspirate samples of patients with active multiple myeloma (MM) compared to those of normal controls. Furthermore, MM patients with advanced aggressive disease had significantly higher levels of IL-6 and TNFα than those with MM in plateau...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Lee, Chansu, Oh, Jeong-In, Park, Juwon, Choi, Jee-Hye, Bae, Eun-Kyung, Lee, Hyun Jung, Jung, Woo June, Lee, Dong Soon, Ahn, Kwang-Sung, Yoon, Sung-Soo
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Hindawi Publishing Corporation 2013
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787550/
https://ncbi.nlm.nih.gov/pubmed/24151609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/580135
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